Lacunar Stroke

Researchers Emma Young and Nina Cron have just recruited their first stroke patient into the study called “DNA Lacunar 2” this week.


What is a Lacunar stroke?

This is a type of ischaemic stroke that occurs when blood flow to one of the small arteries in the brain becomes blocked. This is known as Cerebral Small Vessel Disease (SVD).


How does this affect the patient?

It is the least understood stroke subtype but can leave the patient with disabling symptoms such as limb weakness, paralysis, co-ordination and communication problems which have an acute or long term effect on the person’s health and well-being.


Why is this study being done?

SVD is responsible for about a fifth of all strokes worldwide and is a major cause of vascular cognitive impairment, dementia and often intra-cerebral haemorrhage.

Due to the lack of knowledge surrounding SVD and in particular the pathogenesis we are unable to provide specific therapies to delay the disease progression.

This study aims to use genetics to understand more about this particular type of stroke and may offer the further knowledge we need to be able to treat and most importantly potentially delay the progression of SVD.

The study is aiming to recruit 1000 patients with lacunar strokes, this will be added to a further 2000 allowing 3000 sets of data to be analysed.